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1-15 of 5314 results
Pfizer to acquire Medivation for $14bn
By PBR Staff Writer
Pfizer has agreed to acquire US biopharmaceutical firm Medivation in a transaction valued at about $14bn.
Drug Research > Drug Discovery & Development > News
DS Biopharma launches spin-out firm focused on fibrotic conditions and pulmonary disorders
DS Biopharma has launched a spin-out company focused solely on fibrotic conditions such as non-alcoholic steatohepatitis (NASH) and pulmonary disorders such as chronic obstructive pulmonary disease (COPD) and Idiopathic pulmonary fibrosis (IPF).
Drug Research > Drug Discovery & Development > News
Hemispherx Biopharma forms scientific advisory board to advice on drug development programs
Hemispherx Biopharma has formed a scientific advisory board (SAB) to leverage its member’s scientific and pharmaceutical expertise and advice to advance the Company’s drug development programs by providing guidance on steering the company forward and capitalizing on business opportunities as well as interactions with the Food and Drug Administration.
Drug Research > Drug Discovery & Development > News
Bayer and CRISPR Therapeutics JV starts operations in Massachusetts, US
By PBR Staff Writer
Casebia Therapeutics, the joint venture (JV) between Bayer and gene editing company CRISPR Therapeutics, has commenced its operations in Cambridge, Massachusetts, US.
Drug Research > Drug Discovery & Development > News
Xenetic Biosciences partners with Excivion to develop novel combined Zika and Dengue vaccine
Xenetic Biosciences has commenced a collaboration with Excivion to develop a vaccine against Zika and dengue viruses.
Drug Research > Drug Discovery & Development > News
Caribou Biosciences develops new method to profile CRISPR-Cas9 gene editing outcomes
Caribou Biosciences announced that members of its scientific team have discovered that DNA repair outcomes following Cas9 cleavage of DNA are nonrandom and follow highly reproducible patterns for each target site.
Drug Research > Drug Discovery & Development > News
Study suggests Zika virus may damage adult brain
By PBR Staff Writer
A new study has indicated the Zika virus, which is known to affect unborn babies, may also damage adult brain cells.
Drug Research > Drug Discovery & Development > News
Tioma Therapeutics raises $86m to further develop antibody portfolio
By PBR Staff Writer
Tioma Therapeutics, a venture-stage biopharmaceutical firm focused on the development of anti-CD47 antibodies to treat solid and hematologic cancers, has raised $86m in Series A venture financing.
Drug Research > Drug Discovery & Development > News
NeuroVive Pharmaceutical completes 10% acquisition of Isomerase Therapeutics
NeuroVive Pharmaceutical has completed the second step in the previously announced partial acquisition of the British drug discovery and development company Isomerase Therapeutics.
Drug Research > Drug Discovery & Development > News
Arrowhead Pharmaceuticals closes $45m private offering
Arrowhead Pharmaceuticals (ARWR) has closed a previously announced private offering with a select group of investors that include Orbimed, RA Capital Management, Perceptive Advisors, RTW Investments and other institutional investors.
Drug Research > Drug Discovery & Development > News
Mallinckrodt To Acquire Stratatech
Mallinckrodt has entered into a merger agreement with Stratatech, a privately held regenerative medicine company focused on the development of unique, proprietary skin substitute products.
Drug Research > Drug Discovery & Development > News
AstraZeneca invests another $140m in Moderna Therapeutics
By PBR Staff Writer
AstraZeneca has invested another $140m in Moderna Therapeutics, a US-based biotechnology company focused on the research and development of protein therapies based on novel messenger RNA (mRNA) technology.
Drug Research > Drug Discovery & Development > News
Almac's Colon Cancer Recurrence Assay in Journal of Clinical Oncology
Almac Publish Second Validation of Stage II Colon Cancer Recurrence Assay in the Journal of Clinical Oncology.
Drug Research > Drug Discovery & Development > Press Releases
Almac Group Supports Amicus Therapeutics' Commercial Orphan Drug Product
Almac Group's Integrated Development to Commercialisation Services Support Amicus Therapeutics' First Commercial Orphan Drug Product.
Drug Research > Drug Discovery & Development > Press Releases
Scintilla Pharmaceuticals enters into binding term sheet to buy SCILEX Pharmaceuticals
Scintilla Pharmaceuticals, a subsidiary of Sorrento Therapeutics, has entered into a binding term sheet to acquire SCILEX Pharmaceuticals.
Drug Research > Drug Discovery & Development > News

PBR Supplier Recommendations

Hybrigenics Services - Protein Interactions Expert
Who else knows your protein better than you? Who else knows proteins interactions better than us?... Drug Research > Drug Discovery & Development > Suppliers
LABORATORIOS INIBSA - Pharmaceutical Contract Manufacturing Company
LABORATORIOS INIBSA is a pharmaceutical contract manufacturing company. We have more than 60 years' experience and belong to the INIBSA GROUP. INIBISA supplies products and services to Biotools, Inibsa Dental and Inibsa Hospital, as well as other pharmaceutical companies through our contract manufacturing division. From our facilities in Lliçà de Vall, 20km from Barcelona LABORATORIOS INIBSA currently supplies more than 50 countries worldwide.... Drug Research > Drug Discovery & Development > Suppliers
Chemoswed - Suppliers of Active Pharmaceutical Ingredients
Chemoswed is the reliable Swedish custom synthesis specialist, supplying active ingredients since 1944. With a background in Pharmacia, Chemoswed is since 1996 an independent entity within the DuPont group, offering cost-effective, turn-key solutions to API needs worldwide.We have established unparalleled experience and technology, enabling efficient development and production of quality active pharmaceutical ingredients in quantities from 100 grams to 50 tons.... Drug Research > Drug Discovery & Development > Suppliers
Novo Nordisk Pharmatech A/S - Insulin Human and Benzalkonium Chloride Products
Novo Nordisk Pharmatech A/S is a Novo Nordisk company that specialises in the supply of ingredients for the biopharmaceutical and pharmaceutical industries, such as insulin human for cell culture media and cGMP manufactured quaternary ammonium compounds (usually referred to as quats) such as benzalkonium chloride, cetrimide and cetrimonium bromide.... Drug Research > Drug Discovery & Development > Suppliers
Biovian - cGMP Contract Manufacturing of Biopharmaceuticals
Biovian is a dynamic and effective new generation one-stop-shop CMO in cGMP contract manufacturing of biopharmaceuticals. Biovian's services cover the full range from antigen isolation, expression, vector construction, cell line cultivation, cGMP protein purification to product fill and finish.... Drug Research > Drug Discovery & Development > Suppliers
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PBR White Paper Recommendations

1.5 Specific dsDNA Quantification UV/VIS-based cDrop™ Method vs Picogreen® Fluorescent Assay By Trinean
Precise quantification and normalization of isolated genomic DNA is critical for advanced molecular testing in life science research and molecular diagnostics. UV-Vis based quantification has long been the method of choice, mainly because of its convenience. However, determining the DNA concentration based on the absorbance at 260nm suffers from interference of components such as RNA, proteins and phenols. Alternative methods, such as the PicoGreen® based Quant-iT™ assay, based on fluorescence enhancement upon binding with dsDNA have been developed to address this issue.... Drug Research > Drug Discovery & Development > White Papers 1.3 Micro-volume Protein Quantification using the DropSense96 Droplet Plate Reader By Trinean
The measurement of protein concentration in aqueous samples is an important assay in biochemistry research and protein production facilities. Spectrophotometric protein quantification assays are commonly used methods to rapidly determine the concentration of a protein. They utilize the direct UV absorbance of the protein at 280nm in combination with its extinction coefficient or an indirect dye-based methods like BCA, Lowry and Bradford assays.... Drug Research > Drug Discovery & Development > White Papers 1.2 DropSense96 and its DropPlates, a Versatile Tool for Nucleic Acid and Protein Droplet Quantification By Trinean
As the demand for molecular tests increases, automated systems for biomolecule isolation and sample analysis are becoming popular. These facilitate integration of the complete molecular test in a full automatic set-up with liquid robots and bar-coded sample tracking resulting in a significant higher throughput while minimizing tedious manual repetitive tasks. The Trinean technology is a unique combination of the DropSense96 droplet plate reader, the 96well DropPlate microfuidic consumables and the DropQuant analytical software enabling direct quantification of small biomolecule samples in these high throughput, automated workflow.... Drug Research > Drug Discovery & Development > White Papers 1.14 Droplet UV/VIS Quantification of Native Proteins in Biopharmaceutical Processing By Trinean
Biopharmaceuticals are mainly produced by microbial fermentation or in animal cell cultures. As a consequence, a cascade of procedures including purification and characterization are required throughout the processing chain to obtain the protein at the desired level of purity and potency. Within these processes, quantification of the protein of interest is mandatory at critical steps to maintain confidence in the processing results and fidelity in the end product.... Drug Research > Drug Discovery & Development > White Papers 1.20 Quantification of His-tagged IgG antibodies after IMAC Ni-column purification By Trinean
Trinean introduces a new cDrop™ application suited for the quantification (OD280) of IgG antibodies and derivatives like Fab fragments during purification by IMAC Ni-columns using imidazole-containing buffers.... Drug Research > Drug Discovery & Development > White Papers See more
1-15 of 5314 results