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Drug Discovery & Development
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1-15 of 5354 results
Turing advances several experimental compounds into pre-clinical development
Turing Pharmaceuticals has advanced several experimental compounds into pre-clinical development.
Drug Research > Drug Discovery & Development > News
Allergan to acquire Tobira Therapeutics in $1.7bn deal
By PBR Staff Writer
Allergan has agreed to acquire clinical-stage biopharmaceutical firm Tobira Therapeutics in a deal worth about $1.7bn.
Drug Research > Drug Discovery & Development > News
Alnylam opens new development and commercial hub in Maidenhead, UK
RNAi therapeutics firm Alnylam Pharmaceuticals has opened a new development and commercial hub in Maidenhead, UK.
Drug Research > Drug Discovery & Development > News
Aerie Pharmaceuticals raises $125m in public offerings
Aerie Pharmaceuticals announced the pricing of a registered underwritten public offering of $75m of shares of its common stock at a price to the public of $29.50 per share, before deducting underwriting discounts and commissions and other estimated offering expenses.
Drug Research > Drug Discovery & Development > News
Peloton Therapeutics completes $52.4m Series D financing round
Peloton Therapeutics, a drug discovery and development firm focused on advancing small molecule cancer therapies, has completed a $52.4m Series D financing round.
Drug Research > Drug Discovery & Development > News
Allergan to buy Vitae Pharmaceuticals for $639m
By PBR Staff Writer
Allergan has agreed to acquire US-based clinical-stage biotechnology firm Vitae Pharmaceuticals for about $639m.
Drug Research > Drug Discovery & Development > News
Diabetes startup AnTolRx secures funding from Pfizer, JDRF and Orion Equity
AnTolRx has signed a Series A funding agreement with Pfizer, Orion Equity Partners and JDRF, a global organization funding type 1 diabetes (T1D) research.
Drug Research > Drug Discovery & Development > News
Horizon Discovery, Fulcrum partner for novel CRISPR-based target discovery in genetic diseases
By PBR Staff Writer
UK-based Horizon Discovery Group has partnered with US biotechnology firm Fulcrum Therapeutics for novel CRISPR-based target discovery in genetic diseases.
Drug Research > Drug Discovery & Development > News
Merck discontinues osteoporosis drug development on increased risk of stroke
By PBR Staff Writer
Merck said it would stop the development of its experimental osteoporosis drug, odanacatib, because it carries a higher risk of stroke.
Drug Research > Drug Discovery & Development > News
Taiho Ventures invests in Arcus Biosciences
Taiho Ventures has invested in California-based immuno-oncology firm Arcus Biosciences.
Drug Research > Drug Discovery & Development > News
Takeda gets financial support from US to develop Zika vaccine
By PBR Staff Writer
Japanese drugmaker Takeda Pharmaceutical has won US government funding to develop a vaccine for the mosquito-borne Zika virus.
Drug Research > Drug Discovery & Development > News
Singapore sees first case of pregnant woman with Zika virus
By PBR Staff Writer
Singapore has confirmed its first case of a pregnant woman testing positive for the Zika virus infection, as the number of cases of mosquito-borne virus reached 115 in the country.
Drug Research > Drug Discovery & Development > News

PBR Supplier Recommendations

Hybrigenics Services - Protein Interactions Expert
Who else knows your protein better than you? Who else knows proteins interactions better than us?... Drug Research > Drug Discovery & Development > Suppliers
LABORATORIOS INIBSA - Pharmaceutical Contract Manufacturing Company
LABORATORIOS INIBSA is a pharmaceutical contract manufacturing company. We have more than 60 years' experience and belong to the INIBSA GROUP. INIBISA supplies products and services to Biotools, Inibsa Dental and Inibsa Hospital, as well as other pharmaceutical companies through our contract manufacturing division. From our facilities in Lliçà de Vall, 20km from Barcelona LABORATORIOS INIBSA currently supplies more than 50 countries worldwide.... Drug Research > Drug Discovery & Development > Suppliers
Chemoswed - Suppliers of Active Pharmaceutical Ingredients
Chemoswed is the reliable Swedish custom synthesis specialist, supplying active ingredients since 1944. With a background in Pharmacia, Chemoswed is since 1996 an independent entity within the DuPont group, offering cost-effective, turn-key solutions to API needs worldwide.We have established unparalleled experience and technology, enabling efficient development and production of quality active pharmaceutical ingredients in quantities from 100 grams to 50 tons.... Drug Research > Drug Discovery & Development > Suppliers
Novo Nordisk Pharmatech A/S - Insulin Human and Benzalkonium Chloride Products
Novo Nordisk Pharmatech A/S is a Novo Nordisk company that specialises in the supply of ingredients for the biopharmaceutical and pharmaceutical industries, such as insulin human for cell culture media and cGMP manufactured quaternary ammonium compounds (usually referred to as quats) such as benzalkonium chloride, cetrimide and cetrimonium bromide.... Drug Research > Drug Discovery & Development > Suppliers
Biovian - cGMP Contract Manufacturing of Biopharmaceuticals
Biovian is a dynamic and effective new generation one-stop-shop CMO in cGMP contract manufacturing of biopharmaceuticals. Biovian's services cover the full range from antigen isolation, expression, vector construction, cell line cultivation, cGMP protein purification to product fill and finish.... Drug Research > Drug Discovery & Development > Suppliers
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PBR White Paper Recommendations

1.5 Specific dsDNA Quantification UV/VIS-based cDrop™ Method vs Picogreen® Fluorescent Assay By Trinean
Precise quantification and normalization of isolated genomic DNA is critical for advanced molecular testing in life science research and molecular diagnostics. UV-Vis based quantification has long been the method of choice, mainly because of its convenience. However, determining the DNA concentration based on the absorbance at 260nm suffers from interference of components such as RNA, proteins and phenols. Alternative methods, such as the PicoGreen® based Quant-iT™ assay, based on fluorescence enhancement upon binding with dsDNA have been developed to address this issue.... Drug Research > Drug Discovery & Development > White Papers 1.3 Micro-volume Protein Quantification using the DropSense96 Droplet Plate Reader By Trinean
The measurement of protein concentration in aqueous samples is an important assay in biochemistry research and protein production facilities. Spectrophotometric protein quantification assays are commonly used methods to rapidly determine the concentration of a protein. They utilize the direct UV absorbance of the protein at 280nm in combination with its extinction coefficient or an indirect dye-based methods like BCA, Lowry and Bradford assays.... Drug Research > Drug Discovery & Development > White Papers 1.2 DropSense96 and its DropPlates, a Versatile Tool for Nucleic Acid and Protein Droplet Quantification By Trinean
As the demand for molecular tests increases, automated systems for biomolecule isolation and sample analysis are becoming popular. These facilitate integration of the complete molecular test in a full automatic set-up with liquid robots and bar-coded sample tracking resulting in a significant higher throughput while minimizing tedious manual repetitive tasks. The Trinean technology is a unique combination of the DropSense96 droplet plate reader, the 96well DropPlate microfuidic consumables and the DropQuant analytical software enabling direct quantification of small biomolecule samples in these high throughput, automated workflow.... Drug Research > Drug Discovery & Development > White Papers 1.14 Droplet UV/VIS Quantification of Native Proteins in Biopharmaceutical Processing By Trinean
Biopharmaceuticals are mainly produced by microbial fermentation or in animal cell cultures. As a consequence, a cascade of procedures including purification and characterization are required throughout the processing chain to obtain the protein at the desired level of purity and potency. Within these processes, quantification of the protein of interest is mandatory at critical steps to maintain confidence in the processing results and fidelity in the end product.... Drug Research > Drug Discovery & Development > White Papers 1.20 Quantification of His-tagged IgG antibodies after IMAC Ni-column purification By Trinean
Trinean introduces a new cDrop™ application suited for the quantification (OD280) of IgG antibodies and derivatives like Fab fragments during purification by IMAC Ni-columns using imidazole-containing buffers.... Drug Research > Drug Discovery & Development > White Papers See more
1-15 of 5354 results