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Ethypharm agrees to acquire UK-based Martindale Pharma
Ethypharm has agreed to acquire Martindale Pharma, a UK-based specialty pharmaceutical firm offering essential medicines to more than 50 countries across the world.
Drug Research > Drug Discovery & Development > News
Takeda, Ovid to co-develop rare pediatric epilepsy candidate TAK-935
Takeda Pharmaceutical said its rare pediatric epilepsy candidate TAK-935 will be co-developed through a partnership with Ovid Therapeutics.
Drug Research > Drug Discovery & Development > News
Horizon Discovery broadens gene editing capabilities
Horizon Discovery Group has expanded its gene editing capabilities through the amendment of a pre-existing license with ERS Genomics to include the full commercial rights for the use of CRISPR edited cell lines for the Good Manufacturing Practice (GMP) manufacturing of biotherapeutics.
Drug Research > Drug Discovery & Development > News
Malin buys 33% interest in UK's Wren Therapeutics
By PBR Staff Writer
Irish life sciences firm Malin has acquired a 33% stake in UK biopharmaceutical company, Wren Therapeutics.
Drug Research > Drug Discovery & Development > News
Aptevo Therapeutics receives $20m payment from Emergent BioSolutions
Aptevo Therapeutics has received a $20m cash payment from Emergent BioSolutions pursuant to a promissory note granted as a result of the spin-off of Aptevo from Emergent, effective August 1, 2016.
Drug Research > Drug Discovery & Development > News
Nivalis Therapeutics unveils corporate restructuring
Nivalis Therapeutics, a clinical stage pharmaceutical firm engaged in the development of new solutions for people with cystic fibrosis (CF), announced that its board of directors has approved a restructuring plan as part of its initiative to evaluate strategic alternatives focused on maximizing stockholder value from its clinical assets and cash resources.
Drug Research > Drug Discovery & Development > News
Clinical-stage biopharmaceutical firm OncoImmune raises $15m funding
OncoImmune, a privately-held, clinical-stage biopharmaceutical company that is actively engaged in the discovery and development of novel immunotherapies for cancer, inflammation and autoimmune diseases, has secured $15m in Series A round of fundraising led by 3E Bioventures Capital.
Drug Research > Drug Discovery & Development > News
Merck expands oncology portfolio with four Vertex cancer programs
By PBR Staff Writer
Merck has agreed to license four oncology research and development (R&D) programs from Vertex Pharmaceuticals.
Drug Research > Drug Discovery & Development > News
Zebra Biologics to partner with AbbVie on new antibody therapeutics discovery
Pre-clinical stage biotechnology firm Zebra Biologics has partnered with AbbVie to discover agonist antibody therapeutics for inflammatory diseases.
Drug Research > Drug Discovery & Development > News
Silence Therapeutics acquires minority stake in Arrowhead Pharmaceuticals
Silence Therapeutics has made a $9.6m equity investment in Arrowhead Pharmaceuticals.
Drug Research > Drug Discovery & Development > News
Mast Therapeutics and Savara sign merger deal
Mast Therapeutics and Savara have entered into a definitive merger agreement, under which the stockholders of Savara would become the majority owners of Mast, and the operations of Mast and Savara would be combined.
Drug Research > Drug Discovery & Development > News

PBR Supplier Recommendations

Biovian - cGMP Contract Manufacturing of Biopharmaceuticals
Biovian is a dynamic and effective new generation one-stop-shop CMO in cGMP contract manufacturing of biopharmaceuticals. Biovian's services cover the full range from antigen isolation, expression, vector construction, cell line cultivation, cGMP protein purification to product fill and finish.... Drug Research > Drug Discovery & Development > Suppliers
Hybrigenics Services - Protein Interactions Expert
Who else knows your protein better than you? Who else knows proteins interactions better than us?... Drug Research > Drug Discovery & Development > Suppliers
LABORATORIOS INIBSA - Pharmaceutical Contract Manufacturing Company
LABORATORIOS INIBSA is a pharmaceutical contract manufacturing company. We have more than 60 years' experience and belong to the INIBSA GROUP. INIBISA supplies products and services to Biotools, Inibsa Dental and Inibsa Hospital, as well as other pharmaceutical companies through our contract manufacturing division. From our facilities in Lliçà de Vall, 20km from Barcelona LABORATORIOS INIBSA currently supplies more than 50 countries worldwide.... Drug Research > Drug Discovery & Development > Suppliers
Chemoswed - Suppliers of Active Pharmaceutical Ingredients
Chemoswed is the reliable Swedish custom synthesis specialist, supplying active ingredients since 1944. With a background in Pharmacia, Chemoswed is since 1996 an independent entity within the DuPont group, offering cost-effective, turn-key solutions to API needs worldwide.We have established unparalleled experience and technology, enabling efficient development and production of quality active pharmaceutical ingredients in quantities from 100 grams to 50 tons.... Drug Research > Drug Discovery & Development > Suppliers
Novo Nordisk Pharmatech A/S - Insulin Human and Benzalkonium Chloride Products
Novo Nordisk Pharmatech A/S is a Novo Nordisk company that specialises in the supply of ingredients for the biopharmaceutical and pharmaceutical industries, such as insulin human for cell culture media and cGMP manufactured quaternary ammonium compounds (usually referred to as quats) such as benzalkonium chloride, cetrimide and cetrimonium bromide.... Drug Research > Drug Discovery & Development > Suppliers
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PBR White Paper Recommendations

Biovian's Contract Manufacturing of Biopharmaceuticals By Biovian
Biovian is a one-stop-shop in GMP contract manufacturing of biopharmaceuticals covering services from early development to finished vial.... Drug Research > Drug Discovery & Development > White Papers 1.5 Specific dsDNA Quantification UV/VIS-based cDrop™ Method vs Picogreen® Fluorescent Assay By Trinean
Precise quantification and normalization of isolated genomic DNA is critical for advanced molecular testing in life science research and molecular diagnostics. UV-Vis based quantification has long been the method of choice, mainly because of its convenience. However, determining the DNA concentration based on the absorbance at 260nm suffers from interference of components such as RNA, proteins and phenols. Alternative methods, such as the PicoGreen® based Quant-iT™ assay, based on fluorescence enhancement upon binding with dsDNA have been developed to address this issue.... Drug Research > Drug Discovery & Development > White Papers 1.3 Micro-volume Protein Quantification using the DropSense96 Droplet Plate Reader By Trinean
The measurement of protein concentration in aqueous samples is an important assay in biochemistry research and protein production facilities. Spectrophotometric protein quantification assays are commonly used methods to rapidly determine the concentration of a protein. They utilize the direct UV absorbance of the protein at 280nm in combination with its extinction coefficient or an indirect dye-based methods like BCA, Lowry and Bradford assays.... Drug Research > Drug Discovery & Development > White Papers 1.2 DropSense96 and its DropPlates, a Versatile Tool for Nucleic Acid and Protein Droplet Quantification By Trinean
As the demand for molecular tests increases, automated systems for biomolecule isolation and sample analysis are becoming popular. These facilitate integration of the complete molecular test in a full automatic set-up with liquid robots and bar-coded sample tracking resulting in a significant higher throughput while minimizing tedious manual repetitive tasks. The Trinean technology is a unique combination of the DropSense96 droplet plate reader, the 96well DropPlate microfuidic consumables and the DropQuant analytical software enabling direct quantification of small biomolecule samples in these high throughput, automated workflow.... Drug Research > Drug Discovery & Development > White Papers 1.14 Droplet UV/VIS Quantification of Native Proteins in Biopharmaceutical Processing By Trinean
Biopharmaceuticals are mainly produced by microbial fermentation or in animal cell cultures. As a consequence, a cascade of procedures including purification and characterization are required throughout the processing chain to obtain the protein at the desired level of purity and potency. Within these processes, quantification of the protein of interest is mandatory at critical steps to maintain confidence in the processing results and fidelity in the end product.... Drug Research > Drug Discovery & Development > White Papers See more
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