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Novo Nordisk's Phase IIIb trial of Ryzodeg fails to meet primary endpoint
By PBR Staff Writer
Novo Nordisk has reported results from a 26-week randomized multinational Phase IIIb trial, which showed that Ryzodeg (insulin degludec/insulin aspart) administered twice daily, provides successful glycaemic control with fewer injections than a basal-bolus regimen.
Drug Research > Drug Discovery & Development > News
Boehringer, CureVac to develop next generation lung cancer immunotherapy
By PBR Staff Writer
Boehringer Ingelheim has entered into an exclusive global license and development agreement with CureVac to develop the latter's new investigational therapeutic mRNA vaccine CV9202 to treat lung cancer.
Drug Research > Drug Discovery & Development > News
Lupin and Merck Serono enter into strategic alliance
By PBR Staff Writer
Lupin and Merck Serono have entered into a strategic partnership to support the latter to broaden its general medicines portfolio in emerging markets.
Drug Research > Drug Discovery & Development > News
Cardiorentis announces €45m financing with HealthCare Royalty Partners
By PBR Staff Writer
Cardiorentis AG, a privately held biopharmaceutical company, announced that it has entered into a €45m financing agreement with HealthCare Royalty Partners (HC Royalty), a US based healthcare investment firm.
Drug Research > Drug Discovery & Development > News
Glenmark's TRPA1 Antagonist 'GRC 17536' Shows Positive Data in a Proof of Concept Study
By PBR Staff Writer
Glenmark Pharmaceuticals announced that its first in class Transient Receptor Potential Ankyrin 1 (TRPA1) antagonist, GRC 17536 has shown positive data in a Phase 2a double blind, placebo controlled, multi-centre, proof of concept study conducted on 138 patients in Europe and India.
Drug Research > Drug Discovery & Development > News
Boehringer, Eli Lilly present results from Phase III study of empagliflozin/linagliptin combination tablet for type 2 diabetes
By PBR Staff Writer
Boehringer Ingelheim and Eli Lilly and Company presented results from a 52-week Phase III study that demonstrated sustained efficacy of the investigational empagliflozin/linagliptin combination tablet in adults with type 2 diabetes (T2D) already taking metformin and in those who were previously untreated.
Drug Research > Drug Discovery & Development > News
Alnylam adds HDP treatment ALN-AGT to strengthen pipeline
By PBR Staff Writer
US-based biopharmaceutical firm Alnylam Pharmaceuticals has strengthened its pipeline with the addition of ALN-AGT, a subcutaneously administered RNAi therapeutic targeting angiotensinogen (AGT) indicated to treat hypertensive disorders of pregnancy (HDP), including preeclampsia.
Drug Research > Drug Discovery & Development > News
Cellerant gets $47.5m contract to support development of CLT-008
By PBR Staff Writer
US-based biotechnology firm Cellerant Therapeutics has received $47.5m contract under a second option exercised by the Biomedical Advanced Research and Development Authority (BARDA) to support the continued advanced development of CLT-008.
Drug Research > Drug Discovery & Development > News
Technical Training
Learn the latest tablet technologies and improve your processes through hands-on training and lectures from world-renowned academic and industry experts – in our training centre or onsite at your facility.
Drug Research > Drug Discovery & Development > Products
Metallurgical Services
By utilising the latest methods and technology, Natoli Metallurgy provides valuable resources to aid in material selection, wear testing, and failure analysis of steels used for tooling and any other metal parts used in manufacturing or packaging.
Drug Research > Drug Discovery & Development > Products
Laboratory Services
Natoli Scientific utilises a network of university, consultant and resident resources to investigate problems and offer customers unique solutions to their formulation and tooling requirements.
Drug Research > Drug Discovery & Development > Products
Register Now for Natoli’s 2014 Training Course: Theory & Practice of Modern Tablet Manufacturing, QC/QA
This hands-on course was developed using the latest techniques, theories and processes to train individuals involved with the design, formulation, unit operations, manufacture, quality control/quality assurance, and bioavailability/bioequivalence of pharmaceutical tablets. The course will take place on 21-23 October, 2014.
Drug Research > Drug Discovery & Development > Press Releases
Limited Seating Available for Natoli’s 2014 Hands-On Technical Training Course
Natoli Engineering Company, Inc. will host their most popular technical training course, Basics of tablet manufacturing and troubleshooting, at their state-of-the-art Technical Training Centre in St. Charles, MO. The two-day course was developed using the latest techniques, theories and processes to train tooling technicians, tablet press operators, tablet press maintenance technicians, quality control/quality assurance personnel, research and development, and supervisors. 16-18 September, 2014.
Drug Research > Drug Discovery & Development > Press Releases
Tool Inspection and Database System
The LVS laser inspection device and TM-II database software interface seamlessly to provide the most powerful tool inspection and control system available.
Drug Research > Drug Discovery & Development > Products
Tablet Compression Accessories Catalog
The only comprehensive tableting accessories catalog features hundreds of products to help you clean, lubricate, maintain, store, and analyse your equipment to prolong tool life, support your investment, and increase productivity.
Drug Research > Drug Discovery & Development > Products

PBR Supplier Recommendations

FeF Chemicals - Insulin Human and Benzalkonium Chloride Products
FeF Chemicals is a Novo Nordisk company that specialises in the supply of ingredients for the biopharmaceutical and pharmaceutical industries, such as insulin human for cell culture media and cGMP manufactured quaternary ammonium compounds (usually referred to as quats) such as benzalkonium chloride, cetrimide and cetrimonium bromide.... Drug Research > Drug Discovery & Development > Suppliers
Alpex Pharma - High Quality Formulation Development & Manufacturing Company
Alpex Pharma is a pharmaceutical company active in Research & Development and Production of ODT (Orally Dispersible Tablet) called also "fast melt" and effervescent tablets. Alpex Pharma has developed a unique proprietary covering ODT technology.... Drug Research > Drug Discovery & Development > Suppliers
NNIT - Full-Service IT Consultancy
With 15 years’ experience, NNIT understands the challenges businesses in the life sciences industry are facing. And we have the solutions.... Drug Research > Drug Discovery & Development > Suppliers
PolyPeptide Group - Proprietary and Generic GMP-Grade Peptides
The PolyPeptide Group is a privately-held group of manufacturing companies that focuses on proprietary and generic GMP-grade peptides for the pharmaceutical, cosmetic and biotechnological market.... Drug Research > Drug Discovery & Development > Suppliers
Trinean - UV-VIS Spectral Analysis of DNA/RNA, Protein or Small Compounds
Trinean develops and produces a new approach for high throughput full scan UV-VIS spectral analysis of microliter droplets of DNA/RNA, protein or small compounds. ... Drug Research > Drug Discovery & Development > Suppliers
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PBR White Paper Recommendations

Why You Should be Using Ultrasonic Cleaning By Natoli Engineering Company
Clean punches and dies are essential to maintaining the integrity and efficiency of your tooling investment, as well as the quality of your product. Ultrasonic cleaning has long been considered the most effective, nondestructive way to clean tools – from medical instruments to tablet tooling.... Drug Research > Drug Discovery & Development > White Papers Choose the Right Tooling By Natoli Engineering Company
Choosing the right tooling can increase tablet output, decrease waste and ultimately determine the success of a product launch.... Drug Research > Drug Discovery & Development > White Papers Eight Ways to Reduce Manufacturing Costs By Natoli Engineering Company
It’s no surprise that in today’s economy, companies are facing budget cuts across the board. In an effort to help our customers address these challenges, we put together this list of eight ways to reduce tablet manufacturing costs.... Drug Research > Drug Discovery & Development > White Papers Seven Inspections Points of Tablet Quality By Natoli Engineering Company
Inspecting tooling and press components for wear or defects could be the most important step in improving tablet quality. There are certain inspection points that are easy to overlook yet can cause significant tablet quality issues and limit tool life. Spend a little time checking the following items for wear or defects to quickly increase tablet quality and reduce tooling cost.... Drug Research > Drug Discovery & Development > White Papers IDT Biologika - Pharmaceuticals By IDT Biologika
In the highly specialized world of sterile liquid dosage forms, IDT Biologika is a contract manufacturing organization with the experience, the capability and the commitment to excellence to offer you a strategic advantage in your commercialization process. Our expertise drives our activities into higher-value pharmaceutical and biotechnology applications.... Drug Research > Drug Discovery & Development > White Papers See more
1-15 of 4868 results