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Drug Discovery & Development
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1-15 of 5290 results
Hybrigenics Services Introduces Hybribody
The new All-In-One service for the selection and validation of antibodies derived from a fully synthetic humanized VHH antibody library.
Drug Research > Drug Discovery & Development > Products
Tricida raises $55m for kidney disease treatment
By PBR Staff Writer
Clinical stage, biopharmaceutical firm Tricida has raised $55m in funding for late-stage trials of its lead candidate, TRC101, in patients with kidney disease.
Drug Research > Drug Discovery & Development > News
Vtesse secures $17m in additional Series A funding
Vtesse, a company committed to developing drugs that will benefit patients with extremely rare, life-threatening diseases, has secured $17m in additional Series A funding in support of its global, pivotal clinical trial of VTS-270 for Niemann-Pick Type C1 disease (“NPC”).
Drug Research > Drug Discovery & Development > News
Hybrigenics Services - Protein Interactions Expert
Who else knows your protein better than you? Who else knows proteins interactions better than us?
Drug Research > Drug Discovery & Development > Suppliers
InflaRx raises $34m for phase II development of IFX-1 anti-complement C5a antibody
By PBR Staff Writer
German Biopharmaceutical firm InflaRx has raised $34m in a Series C financing round to advance clinical phase II development of the lead drug candidate IFX-1.
Drug Research > Drug Discovery & Development > News
Synthorx raises $10m to develop and scale novel protein therapeutics
Synthorx has completed a $10m Series B financing, led by RA Capital Management and joined by Series A investors Avalon Ventures and Correlation Ventures.
Drug Research > Drug Discovery & Development > News
VBI Vaccines applies eVLP Platform to develop novel vaccine candidate to prevent Zika virus
VBI Vaccines has applied its clinical-stage eVLP Platform to the development of a novel vaccine candidate to prevent Zika virus infection.
Drug Research > Drug Discovery & Development > News
Vernalis achieves milestone in oncology drug discovery collaboration with Servier
Vernalis and Servier announced the achievement of a new milestone in their first oncology drug discovery collaboration, triggering a payment of €500K to Vernalis.
Drug Research > Drug Discovery & Development > News
Poxel closes €26.5m capital increase
POXEL, a biopharmaceutical company focused on the development of innovative treatments for type 2 diabetes, announced the closing of a capital increase of 3,400,000 new ordinary shares without preferential subscription rights reserved for a category of investors for a total amount of €26.5m.
Drug Research > Drug Discovery & Development > News
Ardelyx agrees to raise $110m in private placement
By PBR Staff Writer
Clinical-stage biopharmaceutical firm Ardelyx has agreed to raise $110m in a private placement.
Drug Research > Drug Discovery & Development > News
Panther Biotechnology starts formal development of Transferrin Doxorubicin conjugate
Panther Biotechnology has initiated the formal drug development process for its lead compound, Transferrin Doxorubicin (TRF-DOX).
Drug Research > Drug Discovery & Development > News
ProMIS starts new program to find novel Alzheimer’s disease targets on toxic strains of protein tau
ProMIS Neurosciences has initiated a program to identify novel therapeutic targets on neurotoxic strains of the protein tau, which, like neurotoxic strains of Amyloid beta (Aβ), are implicated in the development of Alzheimer’s disease (AD).
Drug Research > Drug Discovery & Development > News
Avacta, Glythera collaborate to develop alternatives to antibody drug conjugates
By PBR Staff Writer
Avacta Group and Glythera have partnered to develop a new, highly targeted bio-therapeutics as an alternative to established antibody drug conjugates.
Drug Research > Drug Discovery & Development > News
Abzena and US research institute form immunotherapy joint venture
By PBR Staff Writer
UK life sciences firm Abzena has joined hands with the Texas-based Baylor Scott & White Research Institute (BSWRI) to develop novel immunotherapies for cancer and other diseases.
Drug Research > Drug Discovery & Development > News
Roivant Sciences, Plexcera Therapeutics establish new biopharmaceutical firm Enzyvant Sciences
Roivant Sciences and Plexcera Therapeutics have announced the formation of Enzyvant Sciences, a new biopharmaceutical company focused on the development of recombinant human acid ceramidase (rhAC), an enzyme replacement therapy for the treatment of patients with Farber disease.
Drug Research > Drug Discovery & Development > News

PBR Supplier Recommendations

Hybrigenics Services - Protein Interactions Expert
Who else knows your protein better than you? Who else knows proteins interactions better than us?... Drug Research > Drug Discovery & Development > Suppliers
LABORATORIOS INIBSA - Pharmaceutical Contract Manufacturing Company
LABORATORIOS INIBSA is a pharmaceutical contract manufacturing company. We have more than 60 years' experience and belong to the INIBSA GROUP. INIBISA supplies products and services to Biotools, Inibsa Dental and Inibsa Hospital, as well as other pharmaceutical companies through our contract manufacturing division. From our facilities in Lliçà de Vall, 20km from Barcelona LABORATORIOS INIBSA currently supplies more than 50 countries worldwide.... Drug Research > Drug Discovery & Development > Suppliers
Chemoswed - Suppliers of Active Pharmaceutical Ingredients
Chemoswed is the reliable Swedish custom synthesis specialist, supplying active ingredients since 1944. With a background in Pharmacia, Chemoswed is since 1996 an independent entity within the DuPont group, offering cost-effective, turn-key solutions to API needs worldwide.We have established unparalleled experience and technology, enabling efficient development and production of quality active pharmaceutical ingredients in quantities from 100 grams to 50 tons.... Drug Research > Drug Discovery & Development > Suppliers
Novo Nordisk Pharmatech A/S - Insulin Human and Benzalkonium Chloride Products
Novo Nordisk Pharmatech A/S is a Novo Nordisk company that specialises in the supply of ingredients for the biopharmaceutical and pharmaceutical industries, such as insulin human for cell culture media and cGMP manufactured quaternary ammonium compounds (usually referred to as quats) such as benzalkonium chloride, cetrimide and cetrimonium bromide.... Drug Research > Drug Discovery & Development > Suppliers
Biovian - cGMP Contract Manufacturing of Biopharmaceuticals
Biovian is a dynamic and effective new generation one-stop-shop CMO in cGMP contract manufacturing of biopharmaceuticals. Biovian's services cover the full range from antigen isolation, expression, vector construction, cell line cultivation, cGMP protein purification to product fill and finish.... Drug Research > Drug Discovery & Development > Suppliers
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PBR White Paper Recommendations

1.5 Specific dsDNA Quantification UV/VIS-based cDrop™ Method vs Picogreen® Fluorescent Assay By Trinean
Precise quantification and normalization of isolated genomic DNA is critical for advanced molecular testing in life science research and molecular diagnostics. UV-Vis based quantification has long been the method of choice, mainly because of its convenience. However, determining the DNA concentration based on the absorbance at 260nm suffers from interference of components such as RNA, proteins and phenols. Alternative methods, such as the PicoGreen® based Quant-iT™ assay, based on fluorescence enhancement upon binding with dsDNA have been developed to address this issue.... Drug Research > Drug Discovery & Development > White Papers 1.3 Micro-volume Protein Quantification using the DropSense96 Droplet Plate Reader By Trinean
The measurement of protein concentration in aqueous samples is an important assay in biochemistry research and protein production facilities. Spectrophotometric protein quantification assays are commonly used methods to rapidly determine the concentration of a protein. They utilize the direct UV absorbance of the protein at 280nm in combination with its extinction coefficient or an indirect dye-based methods like BCA, Lowry and Bradford assays.... Drug Research > Drug Discovery & Development > White Papers 1.2 DropSense96 and its DropPlates, a Versatile Tool for Nucleic Acid and Protein Droplet Quantification By Trinean
As the demand for molecular tests increases, automated systems for biomolecule isolation and sample analysis are becoming popular. These facilitate integration of the complete molecular test in a full automatic set-up with liquid robots and bar-coded sample tracking resulting in a significant higher throughput while minimizing tedious manual repetitive tasks. The Trinean technology is a unique combination of the DropSense96 droplet plate reader, the 96well DropPlate microfuidic consumables and the DropQuant analytical software enabling direct quantification of small biomolecule samples in these high throughput, automated workflow.... Drug Research > Drug Discovery & Development > White Papers 1.14 Droplet UV/VIS Quantification of Native Proteins in Biopharmaceutical Processing By Trinean
Biopharmaceuticals are mainly produced by microbial fermentation or in animal cell cultures. As a consequence, a cascade of procedures including purification and characterization are required throughout the processing chain to obtain the protein at the desired level of purity and potency. Within these processes, quantification of the protein of interest is mandatory at critical steps to maintain confidence in the processing results and fidelity in the end product.... Drug Research > Drug Discovery & Development > White Papers 1.20 Quantification of His-tagged IgG antibodies after IMAC Ni-column purification By Trinean
Trinean introduces a new cDrop™ application suited for the quantification (OD280) of IgG antibodies and derivatives like Fab fragments during purification by IMAC Ni-columns using imidazole-containing buffers.... Drug Research > Drug Discovery & Development > White Papers See more
1-15 of 5290 results