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Drug Discovery & Development News

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61-75 of 3796 results
Roche’s Avastin plus chemotherapy gets FDA approval for cervical cancer treatment
By PBR Staff Writer
Roche has received approval from the US Food and Drug Administration (FDA) for Avastin (bevacizumab) in combination with paclitaxel and cisplatin or paclitaxel and topotecan to treat women with persistent, recurrent or metastatic carcinoma of the cervix.
Drug Research > Drug Discovery & Development > News
Nuvilex reports combined results of the initial Phase 1/2 clinical trial and second Phase 2 clinical trial of Cell-in-a-Box
Nuvilex has announced that its partner, Austrianova, has reported the results from the second Phase 2 clinical trial combining the Cell-in-a-Box cellulose-based live cell encapsulation technology plus low doses of the anticancer prodrug ifosfamide in patients with advanced, inoperable cancer has been published in the scientific journal Pharmaceutics.
Drug Research > Drug Discovery & Development > News
Ligand signs license deal with Avion for Captisol
By PBR Staff Writer
Ligand Pharmaceuticals (LGND) has signed a commercial license agreement with Avion Pharmaceuticals to develop and commercialize four Captisol-enabled programs.
Drug Research > Drug Discovery & Development > News
FDA grants fast track status for Agios's AG-221 to treat AML
By PBR Staff Writer
The US Food and Drug Administration (FDA) has granted Fast Track designation to US-based Agios Pharmaceuticals' AG-221, an oral, selective, potent IDH2 mutant inhibitor, to treat patients with acute myelogenous leukemia (AML) that harbor an isocitrate dehydrogenase-2 (IDH2) mutation.
Drug Research > Drug Discovery & Development > News
TNI BioTech signs supplemental collaborative agreement with Hubei Qianjiang Pharmaceutical
TNI BioTech, a biotechnology company pioneering the manufacturing and marketing of innovative therapies for autoimmune diseases in emerging nations, has announced the signing of a supplemental agreement with Hubei Qianjiang Pharmaceutical Co., Ltd (600568.SS) ( Qianjiang) China on behalf of Cytocom, TNI BioTech's wholly owed subsidiary.
Drug Research > Drug Discovery & Development > News
BioCryst gets additional NIAID funding to advance development of BCX4430
BioCryst Pharmaceuticals has announced that the National Institute of Allergy and Infectious Diseases (NIAID) has exercised additional options to conduct Phase 1 clinical human safety trials of an intramuscular formulation of BCX4430, as well as efficacy studies in non-human primates to assess effective dose ranges and dose schedules.
Drug Research > Drug Discovery & Development > News
AstraZeneca releases top-line results from Phase III programme of lesinurad in gout patients
By PBR Staff Writer
AstraZeneca has released positive top-line results from CLEAR1, CLEAR2 and CRYSTAL, the pivotal Phase III clinical trials investigating the potential of lesinurad, a selective uric acid re-absorption inhibitor (SURI), as a combination therapy to treat patients with symptomatic gout.
Drug Research > Drug Discovery & Development > News
GlaxoSmithKline’s Ebola vaccine may enter clinical trials soon
By PBR Staff Writer
British drugmaker GlaxoSmithKline (GSK) spokesperson has said that its experimental Ebola vaccine may enter into clinical trial "later this year."
Drug Research > Drug Discovery & Development > News
Avillion doses first patients in Phase III bfore trial of BOSULIF to treat CML
Avillion, a co-developer of late-stage pharmaceutical assets, has announced that the first patients have been dosed in the United States in a global Phase 3 clinical trial called "BFORE," which is designed to assess the effectiveness and safety of BOSULIF (bosutinib) as a first-line treatment for patients with chronic phase Philadelphia chromosome positive (Ph+) chronic myelogenous leukemia (CML). The first patient was dosed on July 22, 2014.
Drug Research > Drug Discovery & Development > News
TVM Life supports FAAH Pharma in new neuropathic pain treatment
By PBR Staff Writer
TVM Life Science Ventures VII has made an investment into FAAH Pharma to help the company continue the clinical development of a compound with the potential to treat neuropathic pain.
Drug Research > Drug Discovery & Development > News
Idera, TMA to advance clinical development of myositis treatment
By PBR Staff Writer
Idera Pharmaceuticals and The Myositis Association (TMA) have collaborated to advance a new potential treatment approach for polymyositis and dermatomyositis known as Toll-like receptor (TLR) antagonism.
Drug Research > Drug Discovery & Development > News
Neurovance completes patient enrollment in HAL study for centanafadine to treat ADHD
By PBR Staff Writer
Neurovance, a US-based neuroscience-focused company has completed enrollment in a human abuse liability (HAL) study of centanafadine (formerly EB-1020), a new non-stimulant being developed to treat adults with attention deficit hyperactivity disorder (ADHD).
Drug Research > Drug Discovery & Development > News
Cannabis Science in final negotiations to set up first medical cannabis facilities in Canada
By PBR Staff Writer
Cannabis Science, a US-based company specializing in cannabis formulation-based drug development and related consulting, is in the final stages of launching a new joint venture (JV) company.
Drug Research > Drug Discovery & Development > News
Yabao, Changzhou Le Sun Pharmaceuticals to develop early-stage cancer drugs
By PBR Staff Writer
China-based Yabao Pharmaceutical has entered into a strategic partnership with Changzhou Le Sun Pharmaceuticals to co-develop Le Sun's leading PLK/PI3K dual inhibitor LS-008, which currently is under pre-clinical development.
Drug Research > Drug Discovery & Development > News
Daiichi Sankyo, Charleston to develop new hydrocodone products
Daiichi Sankyo and Charleston Laboratories, through its wholly owned subsidiary LOCL Pharma, have entered into a strategic collaboration for the development and U.S. commercialization of Charleston Laboratories' novel hydrocodone combination products, including CL-108, being studied for the treatment of moderate to severe acute pain as well as the reduction of Opioid-Induced Nausea and Vomiting (OINV).
Drug Research > Drug Discovery & Development > News
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