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Drug Discovery & Development News

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91-105 of 3748 results
NCKU Professor discovers drug to inhibit liver cancer
National Cheng Kung University (NCKU), Department of Microbiology and Immunology, Distinguished Professor Dr Hsiao-Sheng Liu and his research team have discovered that the anti-arrhythmic drug Amiodarone can inhibit tumorigenesis of liver cancer through autophagy.
Drug Research > Drug Discovery & Development > News
BMS, Celldex enter clinical trial collaboration to evaluate nivolumab-varlilumab combination
Bristol-Myers Squibb (BMS) and Celldex Therapeutics have entered into a clinical trial collaboration to evaluate the safety, tolerability and preliminary efficacy of nivolumab, Bristol-Myers Squibb’s investigational PD-1 immune checkpoint inhibitor, and varlilumab, Celldex’s CD27 targeting investigational antibody in a Phase 1/2 study.
Drug Research > Drug Discovery & Development > News
DBV Technologies to develop Viaskin Milk for eosinophilic esophagitis treatment
By PBR Staff Writer
France-based DBV Technologies, creator of Viaskin, a new paradigm for the treatment of allergies, has signed a clinical agreement with Dr. Jonathan Spergel at The Children's Hospital of Philadelphia to carry out a clinical trial to develop Viaskin Milk for the treatment of milk-induced eosinophilic esophagitis (EoE) in children.
Drug Research > Drug Discovery & Development > News
Jubilant, Orion enter into drug discovery program in pain management area
By PBR Staff Writer
Jubilant Biosys, Indian subsidiary of Jubilant Life Sciences, and Finish pharmaceutical firm Orion have entered into a drug discovery collaboration to identify small molecule inhibitors in the neuroscience therapeutic area.
Drug Research > Drug Discovery & Development > News
MabVax Therapeutics and Telik sign definitive merger agreement
MabVax Therapeutics, a privately held cancer immunotherapy company, and Telik, aclinical stage oncology drug development company, have entered into a definitive merger agreement.
Drug Research > Drug Discovery & Development > News
Nymox announces completion of second Phase III NX-1207 trial for BPH
Nymox Pharmaceutical has announced that the last enrolled patient has completed participation in the company's pivotal Phase III clinical trial, NX02-0018.
Drug Research > Drug Discovery & Development > News
Janssen announces expanded collaboration with International Partnership for Microbicides
Janssen R&D Ireland (Janssen) has expanded its collaboration with the International Partnership for Microbicides (IPM) for the development and delivery of dapivirine (TMC120) for the prevention of HIV.
Drug Research > Drug Discovery & Development > News
Debiopharm, Yale to develop MIF inhibitors to treat autoimmune, inflammatory diseases
By PBR Staff Writer
Swiss biopharmaceutical firm Debiopharm Group has signed a new license and research agreement with Yale University (Yale), a premier university with a long tradition of basic and clinical biomedical research, to discover MIF inhibitors for the treatment of autoimmune and inflammatory diseases.
Drug Research > Drug Discovery & Development > News
Evotec, Eternygen to discover and develop new metabolic disease therapy
By PBR Staff Writer
German pharmaceutical firms Evotec and Eternygen have entered into a drug discovery collaboration to develop new small molecule inhibitors.
Drug Research > Drug Discovery & Development > News
Regeneron, Avalanche to develop new gene therapy products in ophthalmology
By PBR Staff Writer
Regeneron Pharmaceuticals and Avalanche Biotechnologies have formed a broad collaboration to discover, develop and commercialize new gene therapy products for the treatment of ophthalmologic diseases.
Drug Research > Drug Discovery & Development > News
Auven Therapeutics, Bellus Health announce license agreement with Mount Sinai for Kiacta in sarcoidosis
Auven Therapeutics and Bellus Health have announced that Auven has entered into a license agreement with the Icahn School of Medicine at Mount Sinai in New York, under which the company obtains rights to develop Kiacta (eprodisate) as a treatment for chronic sarcoidosis.
Drug Research > Drug Discovery & Development > News
DSMB recommends stopping Vintafolide PROCEED Phase III trial
Merck and Endocyte have announced that the Data Safety Monitoring Board (DSMB) of the PROCEED trial has completed a pre-specified, interim futility analysis and the DSMB recommended that the trial be stopped because vintafolide did not demonstrate efficacy on the pre-specified outcome of progression-free survival (PFS) in patients with platinum-resistant ovarian cancer.
Drug Research > Drug Discovery & Development > News
FDA issues complete response letter for Plumiaz
Acorda Therapeutics has announced that the US Food and Drug Administration (FDA) has issued a complete response letter (CRL) for the New Drug Application (NDA) for Plumiaz (diazepam) nasal spray for the treatment of people with epilepsy who experience cluster seizures.
Drug Research > Drug Discovery & Development > News
Ruthigen submits IND application to FDA for Phase I/II clinical trial of RUT58-60
By PBR Staff Writer
Ruthigen has submitted an Investigational New Drug (IND) application to the US Food and Drug Administration (FDA) for clinical trial of RUT58-60, a new chemical formulation containing hypochlorous acid (HOCl) with no hypochlorite that utilizes other small molecule stabilizers such as magnesium.
Drug Research > Drug Discovery & Development > News
ANI Pharma, Sofgen Pharma sign agreement to develop ANDA soft gel oral drug product
By PBR Staff Writer
ANI Pharmaceuticals, an integrated specialty pharmaceutical company, and Sofgen Pharmaceuticals, a niche pharmaceutical company, have signed an exclusive licensing, development and supply agreement for the development of an ANDA soft gel oral drug product.
Drug Research > Drug Discovery & Development > News
91-105 of 3748 results