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Drug Discovery & Development News

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91-105 of 3767 results
Agios starts multiple ascending dose Phase I trial of AG-348 to treat PK deficiency
By PBR Staff Writer
Agios Pharmaceuticals has started a multiple ascending dose (MAD) Phase I trial of AG-348 in healthy volunteers for the treatment of pyruvate kinase (PK) deficiency, a rare, hemolytic anemia.
Drug Research > Drug Discovery & Development > News
ScinoPharm to provide API to TaiGen for new stem cell drug
ScinoPharm Taiwan, specializing in the development and manufacture of active pharmaceutical ingredients, and TaiGen Biotechnology have signed a manufacturing contract for the clinical supply of the API of Burixafor, a new chemical entity discovered and developed by TaiGen.
Drug Research > Drug Discovery & Development > News
ArGEN-X, Shire Pharma enter long-term strategic alliance for new therapeutic antibodies
By PBR Staff Writer
arGEN-X, a Dutch biopharmaceutical firm focused on developing differentiated therapeutic antibodies to treat cancer and severe autoimmune diseases, has entered into a long-term strategic alliance with Shire Pharmaceuticals.
Drug Research > Drug Discovery & Development > News
Trevi Therapeutics gets $25m series B financing for development of nalbuphine ER
Trevi Therapeutics, a clinical stage biotechnology company developing Nalbuphine ER for chronic pruritus conditions, has announced a Series B financing of $25m led by TPG Biotech, the life science venture investment arm of TPG, with $15m funded at first closing.
Drug Research > Drug Discovery & Development > News
Asana acquires branded drug discovery platform from Endo Pharmaceuticals
By PBR Staff Writer
Asana BioSciences, a US-based research and development firm specializing in the discovery and development of new chemical and biological entities, has acquired the early stage branded pharmaceutical discovery platform of Endo Pharmaceuticals, a subsidiary of Endo International.
Drug Research > Drug Discovery & Development > News
Genmab, GSK to start studies of subcutaneous ofatumumab for RRMS and NMO
By PBR Staff Writer
Denmark-based Genmab has announced that its collaboration partner GlaxoSmithKline (GSK) has taken the decision to start additional pivotal studies with the subcutaneous formulation of ofatumumab.
Drug Research > Drug Discovery & Development > News
Benitec commences patient dosing with TT-034 in patients with hepatitis C
Benitec Biopharma has dosed the first patient in its 'first in man', Phase I/IIa clinical trial for TT-034, a ddRNAi-based therapeutic, designed to treat and potentially cure hepatitis C (HCV) with a single injection.
Drug Research > Drug Discovery & Development > News
Rodin secures $12.9m Series A financing to develop novel treatments for CNS disorders
Rodin Therapeutics, a biotechnology company applying insights of epigenetics to novel therapeutics for neurological disorders, has closed a $12.9m Series A financing round.
Drug Research > Drug Discovery & Development > News
Array BioPharma, Biogen Idec enter drug discovery collaboration
By PBR Staff Writer
US-based biopharmaceutical firm Array BioPharma has entered into collaboration agreement with Biogen Idec to discover and develop inhibitors targeting a new kinase for the treatment of autoimmune disorders.
Drug Research > Drug Discovery & Development > News
Immune Design's GLAAS discovery platform used in MEDI7510 Phase I trial
Immune Design, a clinical-stage immunotherapy company focused on the development of novel immune-based therapies for cancer and other chronic conditions, has announced that the application of its GLAAS discovery platform in the Phase 1 clinical trial of MEDI7510, an investigational agent for respiratory syncytial virus (RSV) being developed by MedImmune, the global biologics research and development arm of AstraZeneca.
Drug Research > Drug Discovery & Development > News
BMS, Incyte to evaluate combination regimen of two new immunotherapies for multiple cancers
By PBR Staff Writer
Bristol-Myers Squibb (BMS) and Incyte have entered into a clinical trial collaboration to assess the safety, tolerability and preliminary efficacy of a combination regimen of two novel immunotherapies for multiple cancers.
Drug Research > Drug Discovery & Development > News
EMA's CHMP rejects approval of multiple sclerosis drug Nerventra
By PBR Staff Writer
European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) has rejected the development of Nerventra (Laquinimod) for the treatment of relapsing-remitting multiple sclerosis (RRMS) by Israel-based Teva Pharmaceutical and Swedish biotechnology firm Active Biotech.
Drug Research > Drug Discovery & Development > News
Lanthio Pharma gets €3.6m Dutch loan for new lung fibrosis therapy
By PBR Staff Writer
Netherlands-based biopharmaceutical firm Lanthio Pharma has received an Innovation Credit loan of about €3.6m by Dutch Government agency RVO for the development of new therapy for lung fibrosis.
Drug Research > Drug Discovery & Development > News
Sanford-Burnham, Daiichi Sankyo to develop new therapies for cardiovascular-metabolic diseases
By PBR Staff Writer
US-based Sanford-Burnham Medical Research Institute (Sanford-Burnham) and Japanese firm Daiichi Sankyo have entered into a three-year comprehensive alliance for the development of first-in-class therapeutics indicated to treat cardiovascular-metabolic diseases.
Drug Research > Drug Discovery & Development > News
Nuvilex, TD2 begin preparations for US-based studies on symptoms associated with pancreatic cancer
Nuvilex has announced that, together with Translational Drug Development (TD2) in Scottsdale, Arizona, preparations have begun for US-based preclinical and then clinical studies on the unbearable pain and the accumulation of fluid in the abdominal cavity which are two commonly occurring symptoms associated with advanced pancreatic cancer.
Drug Research > Drug Discovery & Development > News
91-105 of 3767 results