Regeneron initiates enrollment in Phase III gout program
Published: 02-Apr-2009
Arcalyst approved in the US for the treatment of cryopyrin-associated periodic syndromes
Regeneron Pharmaceuticals, a biopharmaceutical company, has initiated patient enrollment in the Phase III program evaluating the efficacy and safety of Arcalyst, also known as interleukin-1 trap, in the prevention of gout flares associated with the initiation of urate-lowering drug therapy and in the treatment of acute gout attacks.
This Phase III program with Arcalyst in gout was designed following discussions with the FDA. It will consist of four clinical studies. The North American-based Pre-Surge 1 study and the global Pre-Surge 2 study are each evaluating the number of gout flares per patient over the first 16 weeks of initiation of allopurinol therapy.
The global Surge study in patients experiencing an acute gout attack is evaluating pain during the initial 72 hours of treatment.
Arcalyst is approved in the US for the treatment of cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome and Muckle-Wells syndrome in adults and children 12 and older.
George Yancopoulos, president of Regeneron Research Laboratories, said: This comprehensive Phase III program reflects our enthusiasm for the potential role of Arcalyst therapy in these two gout patient populations. Initial data from this program are expected in 2010.
Network Sites

Suppliers To This Sector
Browse A-Z
Tecnosoft
Monitoring Systems for Temperature, Humidity and Pressure ...
Vetter Pharma International
High-Quality Aseptically Pre-Filled Injection Systems, Cartridges and Vials ...
Lomapharm
Your Competent Partner for Solid and Liquid Pharmaceuticals ...
LyondellBasell
Polyolefins for Healthcare Applications ...
Investigator Location Services
Instant Access to Experienced Investigators ...
Turku Region
A Bright Future in a Great Location ...
White Papers
Browse A-Z
GRACO's New FDA Pumps
The Graco 3150 3A sanitary pump is designed to meet the stringent sanitation requirements ...
GRACO's New Hydra-Clean
The Graco 3150 3A sanitary pump is designed to meet the stringent sanitation requirements ...
GRACO's New 1590 & 3150 Pumps
The Graco 3150 3A sanitary pump is designed to meet the stringent sanitation requirements ...
Water Treatment
From the control room to the downstream processing area and with an eye on utilities servi ...
Customer Testimonial – Astra Zeneca
From the control room to the downstream processing area and with an eye on utilities servi ...
Hygienic Processing
From the control room to the downstream processing area and with an eye on utilities servi ...


Delicious
Digg
Reddit
Stumble
LinkedIn
Mail sent successfully