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Document Compliance Management
A DCM system covers the entire lifecycle of a document with no gaps. As a consequence, the document always remains under the system's watchful eye, even when it is opened, edited or stored on the desktop.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Duolink - Discover More About Proteins and Protein Interactions
The Duolink® approach provides new insights into proteins and protein interactions. For the first time, individual proteins, their interactions and modifications, can be accurately and objectively quantified in unmodified cells and tissues. For more information please download this free brochure.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Excellence in Juvenile Toxicity Testing
MPI Research has a team of experts dedicated to designing and conducting juvenile toxicity testing in various species. The team is composed of distinguished scientists from the department of Developmental and Reproductive Toxicology (DART) at MPI Research whose scientific excellence is recognised throughout the industry.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Exploratory Development Experience in Neuroscience
This free white paper includes information on Focus's medical equipment in neuroscience, their human disease models and examples of studies – designs, indications and recruitment statistics.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Functional Imaging Using Computer Methods to Improve Respiratory Drug Development
Within the pharmaceutical industry it has become more and more apparent that the cost for the development of new products increases while the number of products that reaches the market declines. One of the causes for this phenomenon is the limited sensitivity of existing lung function tests to detect changes in pulmonary function in an early stage. Therefore within the field of respiratory medicine a consensus is starting to form around the need for new outcome parameters.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
GA-Map™ Technology
Genetic Analysis AS has developed a DNA-based platform technology that allows for simultaneous analysis of a large number of similar (but not identical) gene fragments in one reaction. For a technical description please download this free white paper.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Identifying and Exploiting Opportunities for Pharmacogenetics and Other Predictive Factors
Exploristics offer practical analysis tools that are built on basic principles and allow the evaluation of opportunities for PGx. This evaluation can be performed before the initiation of an extensive and costly experiment.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Improved Cell Counting Technology
Improved Cell Counting Technology illustrates three applications for direct determination of cell concentration with the Accuri C6: viability assessment of cultured cell lines, platelet counts in human peripheral blood samples and determination of T-cell numbers in human peripheral blood.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Latin America Emerges as World Competitor for Global Trials Despite Tough Regulatory Environment
This article examines the regulatory atmosphere that prevails throughout Latin America and considers options that can streamline the timely flow of clinical trial materials through the supply chain.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Live Cell Imaging of Drug Effects on Golgi Morpholgy Using the CELLview™ Cell Culture Dish
Fluorescent and time lapse microscopy, advantages of multiplex analysis and the Golgi apparatus. Please donwload this free white paper for more information.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Management and Analysis of Biomarker Data
There is great expectation in the Pharmaceutical Industry that the era of personalised medicine will deliver safer and more effective treatments (Jørgensen & Winther, 2009). This promise is made possible by the emergence of new technologies and data acquisition platforms that can generate enormous amounts of patient-level biomarker data to characterise biological processes and explain response to treatment.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Multi-Parametric Analysis of Aquatic Organisms using Flow Cytometry
Multi-Parametric Analysis of Aquatic Organisms using Flow Cytometry discusses unique features of the Accuri C6 Flow Cytometer System that make it an ideal instrument for aquatic organism analysis. These features include: size, robustness, digital range, and versatility.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Nonclinical Development of Biopharmaceuticals
Fifteen years ago, small molecules (chemically synthesised molecules designed to interact with a specific cellular receptor) represented the majority of pharmaceuticals under development. During the past ten years, however, the number of therapies being developed that fall into the broad category of biopharmaceuticals has exploded, and there are predictions that the majority of therapies developed in the next ten years will fall into this class.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Overcoming the Limitations of Chemical Structure
Biological targets do not recognise a drug's structural make-up. They respond instead to the properties around the drug generated by the structure. We can now generate and compare these property fields and show how they alone eliminate the largest impediments to drug discovery – the time and cost of evaluating activity and the serendipity involved in jumping from one chemical class to another for resolving patent issues, biological cross-reactions, ADMET and alternative clinical applications.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers
Peptides to Non-Peptides: Leads from Structureless Virtual Screening
FieldPrints™ and field-based overlays have shown themselves to be a robust method for locationg new leads for medicinal chemistry programs. Unlike docking protocols, no x-ray protein information is required and only 2D structures are needed for two or more ligands known to act at the same site. Thus, the technique is applicable to many classes of target for which no acceptable lead-finding solution currently exists because the technique is based on the surface properties of molecules.
Drug Research > Drug Discovery & Development > White Papers
Drug Research > Drug Discovery & Development > White Papers